Thermo Fisher Scientific TNFRSF14 Polyclonal Antibody
TNFRSF14 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 사용 가능. Human 시료 반응성. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 세포 내 TNFRSF14 신호전달 및 면역반응 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the carboxy terminus of human TNFRSF14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153713 |
Product Specific Information
- Suggested positive control: Raji cell lysate
- PA5-20236 can be used with blocking peptide PEP-0355.
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily and functions as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV glycoprotein D (gD) to TNFRSF14 facilitates viral entry. The cytoplasmic region interacts with TRAF family members, mediating signal transduction pathways involved in immune activation. Activation in T cells promotes proliferation and cytokine production, enhancing CTL-mediated tumor immunity. Multiple alternatively spliced transcript variants exist, though some full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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