Thermo Fisher Scientific TNFRSF14 Polyclonal Antibody
TNFRSF14 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합. Human과 Mouse 시료 반응. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 sodium azide 포함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
- View 1 publication
Immunohistochemistry (IHC)
- Tested Dilution: 1 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide from near the amino terminus of human TNFRSF14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153929 |
Product Specific Information
- Suggested positive control: mouse thymus tissue lysate
- PA5-20237 can be used with blocking peptide PEP-0356
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily. It acts as a cellular mediator of herpes simplex virus (HSV) entry through binding of HSV glycoprotein D (gD). The cytoplasmic region interacts with TRAF family members, mediating signal transduction pathways that activate immune responses. In T cells, activation of TNFRSF14 stimulates proliferation and cytokine production, contributing to inflammation and enhanced CTL-mediated tumor immunity. Multiple alternatively spliced transcript variants have been described, though some full-length forms remain undetermined.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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