Thermo Fisher Scientific MKL1 Polyclonal Antibody
Human MKL1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 인간 반응성이 확인되었으며, 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 331–543 of MKL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| RRID | AB_2553239 |
Product Specific Information
- Recommended positive controls: human MKL1-transfected 293T cells
- Predicted reactivity: Mouse (87%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by the MKL1 gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation.
It is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus.
This gene is involved in a specific translocation event that creates a fusion with the RNA-binding motif protein-15 gene, associated with acute megakaryocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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