Thermo Fisher Scientific Phospho-BAD (Ser136) Polyclonal Antibody
BAD 단백질의 Ser136 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunohistochemistry에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제 및 1 mg/mL 농도의 액상 형태로 제공. -20°C 보관 권장.
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- 43068-100UL
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence including phosphorylation site of Serine 136 (S-R-S(p)-A-P) derived from mouse BAD and conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | Dulbecco’s PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by BAD is a member of the BCL-2 family, known as regulators of programmed cell death. This protein promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their death repressor activity. Its proapoptotic activity is regulated through phosphorylation involving kinases such as AKT and MAP kinase, and phosphatase calcineurin. Alternative splicing of this gene results in two transcript variants encoding the same isoform.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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