Thermo Fisher Scientific Interleukin-2 (IL-2) Monoclonal Antibody (IL2/3949)
인간 IL-2에 특이적인 마우스 모노클로날 항체로, IHC 및 Peptide Array 등 다양한 응용에 적합. 단백질 A/G로 정제된 액상 형식이며, 4°C에서 보관. 면역학 연구 및 T세포 활성화 관련 연구용으로 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL2/3949 |
| Immunogen | Recombinant fragment (around aa 21–153) of human IL2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine crucial for the proliferation of activated T cells and differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by IL-4 and IL-7.
The IL-2 gene expression in mature thymocytes is monoallelic, representing a unique regulatory mechanism.
Disruption of a gene similar to IL-2 in mice causes an ulcerative colitis-like disease, indicating its essential role in immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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