
Thermo Fisher Scientific TIMM50 Monoclonal Antibody (OTI1E9), TrueMAB
TIMM50 단백질을 인식하는 단클론 항체로 Western Blot에 최적화되어 있습니다. 인간, 마우스, 랫트 시료에 반응하며, E. coli에서 생산된 재조합 단백질을 면역원으로 사용했습니다. 동결건조 형태로 제공되며, 1 mg/mL 농도로 재구성 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 45–353 of human TIMM50 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme encoded by the TIMM50 gene in humans.
Tim50 is a subunit of the Tim23 translocase complex in the inner mitochondrial membrane.
Mutations in TIMM50 are associated with epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria.
Expression of TIMM50 is increased in breast cancer cells and decreased in hypertrophic hearts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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