Thermo Fisher Scientific SHARPIN Monoclonal Antibody (OTI1D11), TrueMAB
인간 SHARPIN 단백질(aa 1-326)을 인식하는 Mouse IgG2a 단일클론 항체입니다. Western blot에 최적화되어 있으며, LUBAC 복합체 관련 NF-κB 및 염증 조절 연구에 적합합니다. 무보존제, 동결건조 형태로 제공되며 -20°C에서 보관합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–326 of human SHARPIN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
SHARPIN is a component of the LUBAC complex, which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates, playing a key role in NF-κB activation and inflammation regulation.
LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1, activating canonical NF-κB and JNK signaling pathways.
This process interferes with TNF-induced cell death, preventing inflammation.
LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3, stabilizing the complex.
Together with FAM105B/otulin, LUBAC regulates canonical Wnt signaling during angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific DPYSL2 Monoclonal Antibody (OTI5D7), TrueMAB
784,000원
Thermo Fisher Scientific
Thermo Fisher Scientific PLA2G3 Monoclonal Antibody (OTI1F4), TrueMAB
784,000원
Thermo Fisher Scientific
Thermo Fisher Scientific SHARPIN Monoclonal Antibody (OTI1D11), TrueMAB
784,000원
Thermo Fisher Scientific
Thermo Fisher Scientific SHARPIN Monoclonal Antibody (OTI2B1), TrueMAB
784,000원
Thermo Fisher Scientific
Thermo Fisher Scientific TIMM50 Monoclonal Antibody (OTI1E9), TrueMAB
784,000원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|