Thermo Fisher Scientific MCP-1 Monoclonal Antibody (24822)
인간 MCP-1/CCL2를 인식하는 마우스 IgG1 단클론 항체. Western blot 및 중화 실험에 적합. 단백질 A로 정제된 액상 형태로 제공되며, 보존제가 포함되지 않음. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific MCP-1 Monoclonal Antibody (Clone 24822)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Neutralization (Neu) | 0.1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 24822 |
| Immunogen | Recombinant human MCP-1/CCL2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1957862 |
Product Specific Information
- Neutralization: Human MCP-1 is tested for its ability to neutralize the chemoattractant activity of recombinant human MCP-1 for human monocytes.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines, characterized by two cysteines separated by a single amino acid.
This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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