Thermo Fisher Scientific GPX1 Polyclonal Antibody
Thermo Fisher Scientific의 GPX1 Polyclonal Antibody는 Human, Mouse, Rat 시료에 반응하며 WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Rabbit IgG 폴리클로날 항체로, 고순도 Affinity Chromatography 정제 제품입니다. -20°C 보관, 연구용 전용입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 100–200 of human GPX1 (NP_0005722) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.55 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804630 |
Product Specific Information
- Immunogen sequence: RPGGGFEPNF MLFEKCEVNG AGAHPLFAFL REALPAPSDD ATALMTDPKL ITWSPVCRND VAWNFEKFLV GPDGVPLRRY SRRFQTIDIE PDIEALLSQG P
- Positive Samples: 293T, Mouse liver, Mouse kidney, Rat liver, Rat spleen
- Cellular Location: Cytoplasm
Target Information
Glutathione peroxidases (Gpxs) are ubiquitously expressed enzymes that catalyze the reduction of hydrogen and organic hydroperoxides by glutathione. Several isoforms exist, differing in structure and localization.
GPx1 (cytosolic/mitochondrial) is a selenium-dependent enzyme, the first discovered in the GPx family. GPx2 is expressed in gastrointestinal epithelium, GPx3 is a plasma form released by the kidney, and GPx4 reduces hydroperoxides in membranes and lipoproteins.
All mammalian GPx family members, except Cys-containing GPx3 and GPx5, possess selenocysteine at the active site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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