Thermo Fisher Scientific Phospho-WIPI2 (Ser413) Polyclonal Antibody
WIPI2 단백질의 Ser413 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal 항체입니다. Western blot 및 IHC(P)에서 사용 가능하며, 인간, 생쥐, 랫트 반응성을 보입니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Thermo Fisher Scientific Phospho-WIPI2 (Ser413) Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human WIPI2 (Accession Q9Y4P8), corresponding to amino acid residues around phosphorylated Ser413 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816153 |
Product Specific Information
Antibody detects endogenous levels of WIPI2 only when phosphorylated at Ser413.
Target Information
WD repeat proteins regulate assembly of multiprotein complexes by providing a beta-propeller platform for protein-protein interactions.
WIPI2 (also known as ATG18B or ATG21) is a human homolog of yeast ATG18, containing three WD repeats and forming a 7-bladed propeller structure.
It interacts with Atg16L and ULK1 and is essential for LC3-positive autophagosome formation.
WIPI2, along with WIPI1, is localized to both plasma and autophagosomal membranes.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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