Thermo Fisher Scientific FREM1 Polyclonal Antibody
FREM1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB와 ICC/IF에 적합합니다. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 부착 및 분화 연구용으로 적합한 고품질 연구용 항체입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the carboxy terminus of human FREM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152870 |
Product Specific Information
- A suggested positive control is K562 cell lysate.
- PA5-20981 can be used with blocking peptide PEP-1095.
Target Information
FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development.
FREM1 functions as an extracellular matrix protein essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation.
It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family.
Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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