Thermo Fisher Scientific GEF-H1 Polyclonal Antibody
Drosophila GEF-H1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관됩니다. Rho GTPase 활성화 연구 및 세포 신호전달 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of Drosophila GEF-H1 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735830 |
Product Specific Information
- Positive Control: CG10188 overexpression fruit fly
- Predicted Reactivity: Drosophila (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases are fundamental to numerous cellular processes initiated by extracellular stimuli acting through G protein–coupled receptors.
GEF-H1 may be involved in:
- Epithelial barrier permeability
- Cell motility and polarization
- Dendritic spine morphology
- Antigen presentation
- Leukemic cell differentiation
- Cell cycle regulation
- Innate immune response
- Cancer
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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