Thermo Fisher Scientific Seryl-tRNA synthetase Polyclonal Antibody
Rabbit polyclonal antibody against human Seryl-tRNA synthetase. Validated for WB, IHC(P), and ELISA. Reacts with human, mouse, and rat samples. Supplied as a liquid in PBS with 50% glycerol, stored at -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–300 of human SARS (NP_0065042) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805401 |
Product Specific Information
Immunogen sequence:
MVLDLDLFRV DKGGDPALIR ETQEKRFKDP GLVDQLVKAD SEWRRCRFRA DNLNKLKNLC SKTIGEKMKK KEPVGDDESV PENVLSFDDL TADALANLKV SQIKKVRLLI DEAILKCDAE RIKLEAERFE NLREIGNLLH PSVPISNDED VDNKVERIWG DCTVRKKYSH VDLVVMVDGF EGEKGAVVAG SRGYFLKGVL VFLEQALIQY ALRTLGSRGY IPIYTPFFMR KEVMQEVAQL SQFDEELYKV IGKGSEKSDD NSYDEKYLIA TSEQPIAALH RDEWLRPEDL PIKYAGLSTC
Positive Samples:
MCF-7, HepG2, HeLa, U-251MG, 293T, Mouse kidney, Mouse brain
Cellular Location:
Cytoplasm
Target Information
Seryl-tRNA synthetase (SerRS) catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction:
- Serine is first activated by ATP to form Ser-AMP.
- Serine is then transferred to the acceptor end of tRNA(Ser).
It may also aminoacylate tRNA(Sec) with serine to form misacylated L-seryl-tRNA(Sec), which is further converted into selenocysteinyl-tRNA(Sec).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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