Thermo Fisher Scientific RRM1 Polyclonal Antibody
Thermo Fisher Scientific의 RRM1 Polyclonal Antibody는 인간 및 마우스 시료에 반응하며, Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합합니다. 친화 크로마토그래피로 정제된 액상 항체로, PBS 및 글리세롤 버퍼에 보관되며 세포질 내 RRM1 단백질 검출에 유용합니다.
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Thermo Fisher Scientific RRM1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 200 µg–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 593–792 of human RRM1 (NP_0010241) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805400 |
Product Specific Information
- Positive Samples: HeLa, SW480, 22Rv1, U-251MG, Mouse thymus, Mouse testis, Mouse spleen
- Cellular Location: Cytoplasm
- Immunogen Sequence:
IRNSLLIAPM PTASTAQILG NNESIEPYTS NIYTRRVLSG EFQIVNPHLL KDLTERGLWH EEMKNQIIAC NGSIQSIPEI PDDLKQLYKT VWEISQKTVL KMAAERGAFI DQSQSLNIHI AEPNYGKLTS MHFYGWKQGL KTGMYYLRTR PAANPIQFTL NKEKLKDKEK VSKEEEEKER NTAAMVCSLE NRDECLMCGS
Target Information
RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme catalyzing the biosynthesis of deoxyribonucleotides from ribonucleotides. It provides the precursors necessary for DNA synthesis and is involved in carcinogenesis and tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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