Thermo Fisher Scientific CXXC5 Polyclonal Antibody
CXXC5 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC에 적합하며 인간, 마우스, 랫트 반응성. 액상 형태, 항원 친화 크로마토그래피로 정제, PBS 완충액에 0.02% sodium azide 포함.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the amino terminus of human CXXC5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154536 |
Product Specific Information
- Suggested positive control: human brain tissue lysate
- PA5-21080 can be used with blocking peptide PEP-1194
Target Information
CXXC5 is a zinc finger protein closely related to the DVL1-binding protein CXXC4 (Idax). Like CXXC4, it modulates the Wnt signaling pathway during development.
CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased AXIN2 levels and enhanced Wnt3a response.
CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, participating in the WNT/β-catenin pathway and embryonic kidney development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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