Thermo Fisher Scientific WIZ Polyclonal Antibody
WIZ 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC에 적합. Human, Mouse, Rat 반응성. Antigen affinity chromatography로 정제된 고품질 항체. 1 mg/mL 농도, PBS buffer 및 sodium azide 포함. 연구용으로만 사용.
- 카탈로그번호
- PA521082
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the carboxy terminus of human TFF3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154149 |
Product Specific Information
- Suggested positive control: Rat lung tissue lysate
- PA5-21082 can be used with blocking peptide PEP-1196
Target Information
WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates that WIZ is ubiquitously expressed.
WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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