Thermo Fisher Scientific TFF3 Polyclonal Antibody
TFF3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 냉장 또는 냉동 보관 권장. 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | 2.5 µg/mL | View 3 publications |
| Immunocytochemistry (ICC/IF) | 2–20 µg/mL | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the carboxy terminus of human TFF3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152862 |
Product Specific Information
- Suggested positive control: rat small intestine tissue lysate
- PA5-21081 can be used with blocking peptide PEP-1195
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds forming the trefoil motif (P-domain) and are clustered in human chromosome 21q22.3.
Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells lining mucus membranes in the large and small intestines and lower respiratory tract.
TFF3 is mainly active as a disulfide-linked homodimer and may promote cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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