Thermo Fisher Scientific CEP78 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CEP78 protein for WB and IP applications. Recognizes residues 639–689 of CEP78. Supplied as liquid, unconjugated form at 0.20 mg/mL concentration. Stored at 4°C, shipped on wet ice, shelf life 1 year.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 639 and 689 of human centrosomal protein 78kDa (CEP78) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
This gene encodes a centrosomal protein required for regulation of centrosome-related events during the cell cycle and for ciliogenesis. The encoded protein has an N-terminal leucine-rich repeat (LRR) domain with six consecutive repeats and a C-terminal coiled-coil domain. It interacts with the catalytic domain of polo-like kinase 4 (PLK4) and colocalizes with PLK4 at the distal end of the centriole. Mutations in this gene lead to defects in primary cilia causing retinal degeneration and sensorineural hearing loss, associated with cone-rod degeneration disease and Usher syndrome. Low expression is linked to poor prognosis in colorectal cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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