Thermo Fisher Scientific Phospho-CHK1 (Ser345) Recombinant Rabbit Monoclonal Antibody (PS01-17)
Phospho-CHK1 (Ser345) 특이적 재조합 토끼 단클론 항체로, 인간 CHK1 단백질의 Ser345 인산화 부위를 인식합니다. Western blot 및 ICC/IF에 최적화되어 있으며, 고순도 Protein A 정제 및 안정적 PBS/BSA/glycerol 포뮬레이션으로 제공됩니다. 연구용으로만 사용 가능합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Thermo Fisher Scientific Phospho-CHK1 (Ser345) Recombinant Rabbit Monoclonal Antibody (PS01-17)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PS01-17 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding Ser345 of human Chk1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2937395 |
Product Specific Information
- Predicted band size: 54 kDa
- Positive Controls: HeLa treated with Etoposide cell lysate, HeLa treated with Hydroxyurea cell lysate, HeLa treated with 4 mM Hydroxyurea for 20 hours
- Subcellular Location: Nucleus, Chromosome, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome
- Sequence Similarities: 100% Mouse/Rat
- Tissue Specificity: Expressed ubiquitously with the most abundant expression in thymus, testis, small intestine, and colon
Target Information
CHEK1 (CHK1) is a serine/threonine protein kinase involved in maintaining genomic integrity by preventing replication when DNA integrity is compromised. It acts as a key mediator in the DNA damage-induced checkpoint network. CHK1 inhibition leads to mitotic catastrophe and apoptosis in p53-deficient cancer cells, making it a promising therapeutic target for cancer treatment, particularly in p53-deficient tumors.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
제품 이미지
(이미지 없음)
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific VEGF Receptor 2 Recombinant Rabbit Monoclonal Antibody (001), FITC
635,400원
Thermo Fisher Scientific
Thermo Fisher Scientific CDX2 Monoclonal Antibody (CL12967)
701,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-CHK1 (Ser345) Recombinant Rabbit Monoclonal Antibody (PS01-17)
705,800원
Thermo Fisher Scientific
Thermo Fisher Scientific Cytokeratin 3 Monoclonal Antibody (AE5)
894,500원
Thermo Fisher Scientific
Thermo Fisher Scientific LAMP1 Monoclonal Antibody (H4A3)
595,300원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|