Thermo Fisher Scientific CD44 Monoclonal Antibody (IM7), Functional Grade, eBioscience
CD44 단백질을 인식하는 IM7 클론의 Rat IgG2b 단일클론 항체로, Flow Cytometry 등 다양한 기능적 분석에 사용 가능. Functional Grade로 제조되어 세포 표면 CD44 검출에 적합하며, 높은 순도와 낮은 엔도톡신 수준을 보장. 연구용으로만 사용.
- 카탈로그번호
- 16-0441-xxx (6개 옵션)
- 판매단위
- pk
카탈로그
6개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD44 Monoclonal Antibody (IM7), Functional Grade, eBioscience
Thermo Fisher Scientific CD44 Monoclonal Antibody (IM7), Functional Grade, eBioscience™
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 5 publications |
| Immunohistochemistry (IHC) | - | View 19 publications |
| Immunocytochemistry (ICC/IF) | - | View 13 publications |
| Flow Cytometry (Flow) | 0.125 µg/test | View 194 publications |
| Neutralization (Neu) | - | View 1 publication |
| Functional Assay | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Fruit fly, Human, Mouse, Non-human primate |
| Host / Isotype | Rat / IgG2b, kappa |
| Recommended Isotype Control | Rat IgG2b kappa Isotype Control (eB149/10H5), Functional Grade, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IM7 |
| Conjugate | Functional Grade |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_2865726 |
Available Formats
- Unconjugated
- Alexa Fluor 532, 700
- APC, APC-eFluor 780
- Biotin
- Brilliant UV (395–737)
- Brilliant Violet (421–711)
- eFluor 450, 506
- FITC
- NovaFluor Blue, Red, UV, Violet, Yellow series
- PE, PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
- PerCP-Cyanine5.5
- Super Bright (436–780)
- Request custom conjugation
Product Specific Information
Description:
The IM7 monoclonal antibody reacts with all isoforms of mouse CD44 (Pgp-1). CD44 is expressed by hematopoietic and non-hematopoietic cells. Bone marrow myeloid cells and memory T cells highly express this antigen, and peripheral B and T cells can upregulate CD44 expression. CD44 functions as an adhesion molecule through its binding to hyaluronate, an extracellular matrix component.
Applications Reported:
IM7 antibody has been reported for use in flow cytometric analysis and complement-dependent cytotoxicity.
Applications Tested:
Tested by flow cytometric analysis of mouse bone marrow cells and splenocytes. Can be used at ≤0.125 µg per test (100 µL final volume). Cell number should be empirically determined (10⁵–10⁸ cells/test). Antibody titration recommended for optimal performance.
Storage and Handling:
Use in a sterile environment.
Filtration: 0.2 µm post-manufacturing filtered.
Purity: >90% (SDS-PAGE).
Endotoxin Level: <0.001 ng/µg antibody (LAL assay).
Aggregation: <10% (HPLC).
Target Information
CD44 is a 100 kDa type I transmembrane glycoprotein widely expressed on human leukocytes, brain white matter, and some epithelial cells. It serves as a receptor for hyaluronic acid (HA), mediating cell-cell interactions, adhesion, and migration. CD44 plays roles in lymphocyte activation, recirculation, and homing, and may be upregulated in certain carcinomas linked to metastasis. Multiple isoforms arise via alternative splicing, contributing to functional diversity. CD44 dysfunction is associated with conditions such as superficial keratitis and lichen sclerosus.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.