Thermo Fisher Scientific Phospho-BAD (Ser112) Recombinant Rabbit Monoclonal Antibody (BADS112-B9), PE
PE 형광 표지된 Phospho-BAD (Ser112) 항체로 인간, 마우스, 랫트 시료에 반응합니다. Flow Cytometry에 최적화된 형광 항체이며, 단클론 재조합 형태로 높은 특이성과 재현성을 제공합니다. 단백질 인산화 연구에 적합합니다.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, lambda |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BADS112-B9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser112 of human phospho BAD |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897253 |
Additional Formats
Target Information
The protein encoded by BAD is a member of the BCL-2 family, known to regulate programmed cell death. BAD promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their death repressor activity. Its proapoptotic activity is regulated through phosphorylation by kinases such as AKT and MAP kinase, and dephosphorylation by calcineurin. Alternative splicing produces two transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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