Thermo Fisher Scientific UFD1 Polyclonal Antibody
Thermo Fisher Scientific의 UFD1 다클론 항체는 인간 UFD1L 단백질의 257–307 잔기 영역을 면역원으로 제작된 Rabbit IgG 폴리클론 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, Mouse와 Rat에서도 반응이 예측됩니다. 액상 형태로 제공되며 4°C에서 보관합니다.
- 카탈로그번호
- A301876Ax (2개 옵션)
- 판매단위
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카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific UFD1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 257 and 307 of Human ubiquitin fusion degradation 1 (UFD1L, UniProt ID: Q92890-2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
Ubiquitin-mediated proteolysis requires the transfer of ubiquitin (Ub) to lysine groups on selected cellular proteins, leading to their degradation by the 26S proteasome. Ub-fusions are processed by Ub-specific proteases (UBps) or by the Ub-fusion degradation (UFD) pathway. UFD1, initially identified in yeast S. cerevisiae, has a human homolog UFD1L that modulates degradation of Ub-fusions containing substitutions at Gly76. Mutations in the UFD1 gene are associated with CATCH22 syndrome, characterized by cardiac defects, cleft palate, and hypocalcemia, indicating a role in developmental processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: A301-876A-M_UFD1L_Q92890-2_Rabbit.svg, A301-876A-M_UFD1L_Q92890-2_Rabbit_PDP.jpeg)
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