Thermo Fisher Scientific CFTR VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1042)
CFTR 단백질을 표적으로 하는 알파카 유래 재조합 단일클론 항체입니다. ELISA 등 면역분석에 적합하며, CHO 세포에서 발현된 VHH 형식 항체입니다. 1 mg/mL 농도로 제공되며, 금속 킬레이트 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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- pk
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Thermo Fisher Scientific CFTR VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1042)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1042 |
| Immunogen | Recombinant Human CFTR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Cystic Fibrosis (CF) is a common lethal genetic disease caused by mutations of the gene coding for the cystic fibrosis transmembrane conductance factor (CFTR), a cAMP-regulated chloride channel. Approximately 70% of all CF cases involve a deletion of phenylalanine at position 508 (ΔF508), resulting in abnormal chloride transport. Despite its lethality, CF remains prevalent. One hypothesis suggests that Salmonella typhi utilizes CFTR to enter intestinal epithelial cells, and ΔF508 heterozygote and homozygote mice show 86% and 100% reductions in S. typhi intestinal submucosal uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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