Thermo Fisher Scientific CHRM2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1214)
Thermo Fisher Scientific의 CHRM2 VHH-8His-Cys-tag 항체는 인간 CHRM2 단백질을 타깃으로 하는 알파카 유래 재조합 단일클론 항체입니다. Flow Cytometry 및 Radioimmune Assay에 적합하며, CHO 세포에서 발현된 고순도 항체로 안정적인 연구용 시약입니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Radioimmune Assays (RIA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1214 |
| Immunogen | Recombinant Human CHRM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release. The M2 receptor also mediates smooth muscle contractility. In Alzheimer’s disease (AD), selective loss of M2 subtype receptors occurs in cortical and hippocampal regions. Increased M2 receptor heterozygosity has been associated with depression in women. The M2 receptor is expressed in various brain regions including cerebellum, cerebral cortex, hippocampus, medulla, striatum, thalamus, and in lung and prostate.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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