Thermo Fisher Scientific XPB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human ERCC3(Accession P19447), corresponding to amino acid residues D33-H83. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:XPB,uniProtId:P19447-1,ncbiNodeId:9606,antigenRange:33-83,antigenLength:782,antigenImageFileName:PA5-104396_XPB_P19447-1_Rabbit.svg,antigenImageFileNamePDP:PA5-104396_XPB_P19447-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2853703

Product Specific Information

Antibody detects endogenous levels of total ERCC3.

Target Information

The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH, and is involved in early steps of the nucleotide excision repair (NER) pathway. Two distinct clinical phenotypes, xeroderma pigmentosum associated with Cockayne`s syndrome (XP/CS) and trichothiodystrophy (TTD), can be due to mutations in the XPB gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.