Thermo Fisher Scientific Adenylate Kinase 1 Polyclonal Antibody
Rabbit 폴리클로날 항체로 Adenylate Kinase 1 단백질을 검출. Western blot 및 IHC(Paraffin) 실험에 적합. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제 제품으로 연구용에 최적화.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human AK1 (Accession P00568), corresponding to amino acid residues G110–V160 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853701 |
Product Specific Information
Antibody detects endogenous levels of total AK1.
Target Information
Adenylate kinase is an enzyme that regulates the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides.
Three isozymes of adenylate kinase have been identified in vertebrates: AK1, AK2, and AK3.
- AK1: Found in cytosol of skeletal muscle, brain, and erythrocytes.
- AK2 & AK3: Found in mitochondria of tissues such as liver and heart.
AK1 is associated with a rare genetic disorder causing nonspherocytic hemolytic anemia, where a mutation in the AK1 gene reduces the catalytic activity of the enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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