Thermo Fisher Scientific ABCG8 Polyclonal Antibody
ABCG8 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 액상형 항체이며, PBS/glycerol buffer에 보존. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ABCG8 (Accession Q9H221), corresponding to amino acid residues G289–R339 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853704 |
Product Specific Information
This antibody detects endogenous levels of total ABCG8.
Target Information
ATP-binding cassette (ABC) transporter genes regulate the amount of dietary cholesterol retained in the body.
ABCG8, highly expressed in the liver and intestine, cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols.
Mutations in this transporter can lead to sterol accumulation and disorders such as atherosclerosis or sitosterolemia, characterized by hyperabsorption of sterols and inability to excrete them into bile.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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