Thermo Fisher Scientific H-cadherin Recombinant Rabbit Monoclonal Antibody (JB14-48)
H-cadherin 단백질을 인식하는 토끼 리콤비넌트 단클론 항체. Western blot 및 IHC(P)에서 검증됨. 고순도 Protein A 정제, 1 mg/mL 농도. 인체 반응성, TBS 버퍼에 40% 글리세롤 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50–1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB14-48 |
| Immunogen | Recombinant protein within Human H Cadherin aa 81–220 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848618 |
Product Specific Information
Positive Control: Rat skeletal muscle tissue, human kidney tissue, human fetal skeletal muscle tissue, mouse heart tissue.
Target Information
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs. It interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (FAST-1). Reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene are associated with increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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