Thermo Fisher Scientific Desmoglein 1 Recombinant Rabbit Monoclonal Antibody (JB19-46)
Desmoglein 1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 IHC(P)에서 검증됨. 인간 시료에 반응하며, Protein A로 정제된 1 mg/mL 액상 형태. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB19-46 |
| Immunogen | Synthetic peptide within Human DSG1 aa 1,000–1,049 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848622 |
Product Specific Information
Positive Control: Human colon cancer tissue, human skin tissue, human uterus tissue, mouse skin tissue.
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These desmoglein genes are located in a cluster on chromosome 18. Desmoglein 1 is identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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