Thermo Fisher Scientific BCL6 Recombinant Rabbit Monoclonal Antibody (JB18-48)
BCL6 단백질을 검출하기 위한 토끼 단클론 항체. Western blot에 최적화되어 있으며 인간 시료에 반응. HEK293 세포에서 발현된 재조합 항체로 높은 특이성과 재현성을 제공. 단백질 A로 정제되어 높은 순도 보장.
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Applications
- Western Blot (WB): 1:1,000–1:5,000
- Positive Control: SiHa, NIH-3T3
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB18-48 |
| Immunogen | Synthetic peptide within Human Bcl-6 (aa 657–706) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848620 |
Product Specific Information
- Positive control: SiHa, NIH-3T3.
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and such rearrangements have been detected in 33–45% of diffuse large B cell lymphomas.
Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas, and in nodular, lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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