Thermo Fisher Scientific CD266 Polyclonal Antibody
Thermo Fisher Scientific의 CD266 Polyclonal Antibody는 Mouse 시료에 반응하는 Goat 유래 다클론 항체입니다. WB, IHC(F), Flow Cytometry, ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. Lyophilized 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
| ELISA | 0.1–0.4 µg/mL (Detection), 0.2–0.8 µg/mL (Capture) |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse TWEAKR/TNFRSF12 (Glu28–Trp79) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605591 |
Product Specific Information
- In sandwich ELISAs, less than 2% cross-reactivity with recombinant human TWEAK R is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in transformed cell lines. A receptor for TWEAK, known as TweakR, was isolated by expression cloning from a HUVEC cell cDNA library. TweakR is a small protein belonging to the TNF receptor superfamily and can initiate proliferative signaling by binding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in the aorta and liver, and may play a role in vascular cell migration and angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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