
Thermo Fisher Scientific Myotilin Monoclonal Antibody (OTI5E11)
Myotilin 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot과 IHC(Paraffin) 실험에 적합합니다. 인간 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E11 |
| Immunogen | Full length human recombinant protein of MYOT produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724779 |
Target Information
This gene encodes a cytoskeletal protein that plays a significant role in the stability of thin filaments during muscle contraction. It binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene are associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants have been described, though the full-length nature of some remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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