Thermo Fisher Scientific ACVRL1 Monoclonal Antibody (OTI5C2)
ACVRL1 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. 인간 시료 반응성, 액상 형태로 제공되며 1 mg/mL 농도. PBS/BSA/glycerol 버퍼에 보관, -20°C에서 안정적 저장 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–119 of ACVRL1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723837 |
Target Information
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It contains a conserved serine-threonine kinase subdomain, a glycine- and serine-rich GS domain preceding the kinase domain, and a short C-terminal tail.
Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2 and have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by abnormal bone formation in soft tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: MA5-27180_ACVRL1_P37023-1_House_mouse.svg, MA5-27180_ACVRL1_P37023-1_House_mouse_PDP.jpeg)
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