Thermo Fisher Scientific Calcitonin (CALCA) Monoclonal Antibody (OTI2D12), TrueMAB
인간 Calcitonin (CALCA)을 인식하는 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 연구용으로 세포 내 Calcitonin 발현 및 C-cell 관련 병리 분석에 적합.
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Thermo Fisher Scientific Calcitonin (CALCA) Monoclonal Antibody (OTI2D12), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D12 |
| Immunogen | Synthetic peptide sequence |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Peptide sequence:
CGNLST CMLGTYTQDF NKFHTFPQTA IGVGAP
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Calcitonin is a 32-amino-acid peptide localized in the C cells of normal and hyperplastic thyroid tissue.
Staining for calcitonin aids in identifying C-cell proliferative abnormalities, including C-cell hyperplasia and invasive tumors.
In medullary thyroid carcinoma, calcitonin staining shows a fine granular cytoplasmic pattern, and amyloid deposits may exhibit variable calcitonin activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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