Thermo Fisher Scientific IGF2 Polyclonal Antibody
Mouse IGF2 단백질을 인식하는 Goat Polyclonal 항체로, Western blot, ELISA, Neutralization assay에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 보존제 없이 PBS 버퍼에 함유. 연구용으로만 사용.
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- PA124774
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL |
| ELISA (ELISA) | 0.5–1 µg/mL |
| Neutralization (Neu) | 1.5–4.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified recombinant mouse insulin-like growth factor II, expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose, 0.1% BSA |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2233444 |
Product Specific Information
PA1-24774 detects IGF2 from mouse samples.
Target Information
Insulin-like Growth Factors (IGFs) are mitogenic polypeptide growth factors that promote proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are mainly produced by the liver but can also be synthesized by other tissues at specific developmental stages.
They belong to the insulin gene family, which includes insulin and relaxin, and share structural and functional similarities with insulin but exhibit stronger growth-promoting activity. IGF-II expression is influenced by placental lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), with IGF-II also capable of signaling through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are produced by proteolytic processing of inactive precursors containing N- and C-terminal propeptide regions.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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