Thermo Fisher Scientific IFN beta Polyclonal Antibody
Human IFN-beta에 특이적인 Goat Polyclonal Antibody로 Western blot 및 Neutralization assay에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 용액 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–2 µg/mL |
| Neutralization (Neu) | 0.05–0.20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified, recombinant human IFN-beta, expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_794534 |
Product Specific Information
PA1-24778 has been successfully used in Western blot procedures, where a band of approximately 224 kDa is predicted to be detected.
Target Information
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit tumor development. IFN-beta binding activates tyrosine kinases Jak1 and Tyk2, leading to phosphorylation of STAT transcription factors and expression of immune response genes. Several toll-like receptors (TLRs) also stimulate IFN-beta production. Clinically, IFN-beta is used for treatment of tumors, infections, and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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