Thermo Fisher Scientific CD23 Monoclonal Antibody (EBVCS2), Super Bright 600, eBioscience
인간 CD23 단백질을 인식하는 EBVCS2 클론 단일클론 항체로, Super Bright 600 형광체로 표지되어 유세포 분석(Flow Cytometry)에 적합합니다. B세포 활성화 연구에 유용하며, 낮은 비특이적 결합과 높은 형광 안정성을 제공합니다.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD23 Monoclonal Antibody (EBVCS2), Super Bright 600, eBioscience
Applications
- Flow Cytometry (Flow): 5 µL (0.25 µg)/Test
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Super Bright™ 600, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | EBVCS2 |
| Conjugate | Super Bright™ 600 |
| Excitation / Emission Max | 414 / 601 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2734924 |
Additional Formats
- Unconjugated
- APC
- APC-eFluor 780
- Brilliant UV 805
- eFluor 450
- FITC
- NovaFluor Blue 660-120S
- NovaFluor Blue 690
- NovaFluor Red 685
- NovaFluor Red 700
- NovaFluor Red 755
- NovaFluor Yellow 610
- NovaFluor Yellow 660
- NovaFluor Yellow 700
- NovaFluor Yellow 755
- PE
- PE-Cyanine7
- PE-eFluor 610
- PerCP-Cyanine5.5
- Super Bright 436
- Super Bright 702
- Request custom conjugation
Product Specific Information
The EBVCS2 monoclonal antibody reacts with human CD23, a 45 kDa type II transmembrane glycoprotein. CD23 is expressed on mature B cells, mantle zone B cells, follicular dendritic cells, and at low levels on T, NK, Langerhans cells, and platelets. Expression increases upon B cell activation, and soluble forms are biologically active. CD23 is a low-affinity receptor for IgE and plays a role in regulating IgE response and B cell activation. CD21 and the α-subunit of CD11b/CD11c bind to CD23.
Applications Reported: Flow cytometric analysis.
Applications Tested: Pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. Use 5 µL (0.25 µg) per test (100 µL final volume, 10⁵–10⁸ cells/test).
Super Bright 600:
- Excitation: 405 nm
- Emission: 600 nm
- Recommended filter: 610/20 bandpass
- Use Super Bright Complete Staining Buffer (Product # SB-4401) to minimize non-specific polymer interactions.
- Light sensitive; protect from light.
- Fixation: Samples can be stored in IC Fixation Buffer (Product # 00-8222) or 1-step Fix/Lyse Solution (Product # 00-5333) for up to 3 days at 4°C in the dark.
Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company.
Target Information
CD23 is a 45 kDa glycoprotein found on subsets of peripheral blood and tonsil B cells, and strongly expressed on EBV-transformed B lymphoblasts. It functions as a low-affinity IgE receptor and is involved in B cell growth, differentiation, and IgE production. Soluble CD23 acts as a mitogenic factor. Abnormal CD23 expression is associated with chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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