Thermo Fisher Scientific Phospho-eNOS (Ser1177) Monoclonal Antibody (15E2)
Phospho-eNOS (Ser1177) 단일클론 항체(15E2)는 eNOS의 Ser1177 인산화 형태를 특이적으로 인식합니다. Western blot 및 ELISA에 적용 가능하며, 인간 시료에서 검증되었습니다. 비결합 액상 형태로 -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
- View 2 publications
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 15E2 |
| Immunogen | Phosphopeptide derived from the region of endothelial nitric oxide synthase (eNOS) that contains serine 1177, conjugated to KLH. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | -20°C |
| Shipping conditions | Dry ice |
| RRID | AB_2533628 |
Target Information
Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission, and cytotoxicity can all be potentiated through cellular response to NO.
NO production is mediated by members of the nitric oxide synthase (NOS) family, which catalyze the oxidation of L-arginine to produce L-citrulline and NO.
Three NOS isoforms have been identified:
- Brain or neuronal NOS (b/nNOS, type I)
- Endothelial cell NOS (eNOS, type III)
- Inducible NOS (iNOS, type II)
All NOS isoforms contain calmodulin, NADPH, FAD, and FMN binding domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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