
Thermo Fisher Scientific OPRK1 Polyclonal Antibody
Thermo Fisher Scientific의 OPRK1 Polyclonal Antibody는 마우스 및 랫트 시료에 반응하며 Western blot, IHC, ICC/IF 분석에 적합합니다. 항원 친화 크로마토그래피로 정제된 Rabbit IgG 폴리클로날 항체로, 비결합형 액상 형태이며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 6 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:250 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | The antiserum was produced against a chemically synthesized peptide derived from the internal region of the mouse k-opioid receptor. The sequence is conserved in rat. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.3, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533627 |
Target Information
This gene encodes an opioid receptor, a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands and various synthetic opioids. Ligand binding inhibits adenylate cyclase activity and neurotransmitter release. This receptor is involved in pain perception and mediates the hypolocomotor, analgesic, and aversive effects of synthetic opioids. Variations in this gene are associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been identified. Recent research suggests translational readthrough results in an additional C-terminally extended isoform via an alternative in-frame translation termination codon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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