Thermo Fisher Scientific PTP1B Polyclonal Antibody
PTP1B 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 인간 단백질에 반응하며 4°C에서 보관.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 385 and 435 of Human protein tyrosine phosphatase 1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
PTP1B (PTPN1) is a tyrosine-protein phosphatase that regulates the endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK, thereby inactivating its kinase activity. PTP1B also participates in CKII- and p60c-src-induced signaling cascades, regulates EFNA5-EPHA3 signaling for cell reorganization and repulsion, and modulates hepatocyte growth factor receptor (MET) signaling through dephosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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