Thermo Fisher Scientific POLR3D Polyclonal Antibody
Human POLR3D 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 4°C 보관. 연구용으로만 사용.
- 카탈로그번호
- A302296A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 348 and 398 of Human DNA-directed RNA polymerase III subunit D |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse.
Target Information
This gene encodes a protein that interacts with the N-terminal region of BRCA1. It shares homology with the two most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in proteins that regulate cell growth, including tumor suppressor genes and proto-oncogenes. This protein also contains three tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, suggesting that formation of a stable complex between these proteins may be essential for BRCA1 tumor suppression. This protein may be a target of oncogenic mutations in breast or ovarian cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: A302-296A_POLR3D_P05423-1_Rabbit.svg, A302-296A_POLR3D_P05423-1_Rabbit_PDP.jpeg)
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