
Thermo Fisher Scientific Human ApoE2 Recombinant Protein, PeproTech
인간 ApoE2 재조합 단백질로 지질 대사 연구에 적합. E. coli 발현 시스템 사용, 34.3 kDa 크기 및 300 아미노산 잔기 포함. ≥90% 순도, 내독소 <1 EU/µg. 동결건조 형태로 제공되며 -20°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- 350-12-01M
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Not specified
- View 1 publication
ELISA
- Tested Dilution: Not specified
- View 1 publication
Functional Assay
- Assay-dependent
- View reference
In vitro Assay (IV)
- Tested Dilution: Not specified
- View 4 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKCL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH |
| Molecular Weight | 34.3 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 90% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <1 EU/µg |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
Product Specific Information
Recombinant Human ApoE2 is a 34.3 kDa protein containing 300 amino acid residues.
This product is shipped at ambient temperature.
For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism.
These proteins help solubilize lipids, maintain lipoprotein structural integrity, act as ligands for lipoprotein receptors, and regulate enzymes involved in lipid metabolism.
ApoE is produced mainly in the liver and brain, and also in other organs.
It is a key component of all plasma lipoproteins and mediates uptake of chylomicron remnants via ApoE receptors and LDL receptors (apo B/E).
Defects in ApoE can cause hyperlipoproteinemia type III.
ApoE has three major isoforms: E2, E3, and E4, differing by a single amino acid substitution.
Compared to E3 and E4, E2 has the lowest receptor binding affinity and is associated with lower total cholesterol and LDL levels, but higher ApoE levels.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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