
Thermo Fisher Scientific SCD Polyclonal Antibody
SCD 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 사용 가능. 인간 및 다양한 종에서 반응 예측. 고농도 액상 형태로 제공되며 4°C 또는 -20°C에서 보관. 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of human SCD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2183105 |
Product Specific Information
- Recommended positive controls: human liver, Jurkat
- Predicted reactivity: Cow (92%), Dog (85%), Goat (85%), Guinea Pig (85%), Mouse (77%), Rat (77%), Sheep (85%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid influences cell growth and differentiation by affecting membrane fluidity and signal transduction.
Four SCD isoforms (Scd1–Scd4) have been identified in mouse, while only two (SCD1 and SCD5) exist in humans. SCD1 shares about 85% amino acid identity with all four mouse SCD isoforms and with rat Scd1 and Scd2. SCD5 shows limited homology with rodent SCDs and appears unique to primates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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