
Thermo Fisher Scientific RNF12 Polyclonal Antibody
RNF12 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 IHC(P) 실험에 적합합니다. Rabbit IgG로 제조되었으며, 1 mg/mL 농도의 액상 형태입니다. 다양한 종에서 높은 반응성을 보이며 연구용으로 사용됩니다.
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Thermo Fisher Scientific RNF12 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of human RNF12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2181963 |
Product Specific Information
- Recommended positive control: Jurkat
- Predicted reactivity: Cow (100%), Dog (100%), Guinea Pig (93%), Horse (100%), Mouse (93%), Pig (100%), Rabbit (100%), Rat (93%), Yeast (89%), Zebrafish (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RNF12 is a RING-H2 zinc finger protein and functions as a ubiquitin protein ligase targeting LIM domain binding 1 (LDB1/CLIM), leading to proteasome-dependent degradation of LDB1. RNF12 and LDB1 act as co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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