Thermo Fisher Scientific Laminin-221 Recombinant Rabbit Monoclonal Antibody (17H4L1)
Laminin-221 단백질을 인식하는 재조합 토끼 단클론 항체. 인간 시료에 반응하며, 원숭이·양·고양이·소에서도 예측 반응. 높은 특이성과 일관된 로트 간 품질 제공. 단기 4°C, 장기 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 17H4L1 |
| Immunogen | Protein corresponding to Human LAMA4 (aa 1300–1500) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633075 |
Product Specific Information
This antibody is predicted to react with Monkey, Sheep, Cat, and Bovine.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The specific antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened to select the best candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
Laminin is a non-collagenous protein found in basement membranes. It has a cross-like structure consisting of one long arm (400 kD) and three short arms (200 kD).
Antibodies to laminin localize exclusively in basement membranes, with stronger reactivity in the lamina lucida adjacent to the cell membrane. Laminin binds to type IV collagen and plays a crucial role in cell adhesion and attachment both in vivo and in vitro.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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