Thermo Fisher Scientific FKBP5 Recombinant Rabbit Monoclonal Antibody (6H8L4)
FKBP5 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 면역세포염색에 적합합니다. 높은 특이성과 재현성을 제공하며, 인간, 마우스, 랫드에 반응합니다. 단백질 A로 정제된 액상 형태로 안정적 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6H8L4 |
| Immunogen | Protein corresponding to Human FKBP5 (aa 298–447) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633074 |
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Rabbit, and Sheep.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
FKBP5 is a member of the immunophilin protein family, which participates in immunoregulation and cellular processes involving protein folding and trafficking.
It functions as a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin, mediating calcineurin inhibition.
FKBP5 interacts with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein.
The FKBP5 gene has multiple polyadenylation sites, and alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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