Thermo Fisher Scientific NUP210L Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human NUP210L. Recombinant protein control fragment (Product #RP-106144). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NUP210L,uniProtId:Q5VU65-1,ncbiNodeId:9606,antigenRange:1305-1432,antigenLength:1888,antigenImageFileName:PA5-65465_NUP210L_Q5VU65-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65465_NUP210L_Q5VU65-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663584

Product Specific Information

Immunogen sequence: PINSQLKLHTN REGAAFVSSR VLKCFPNSSV IEEDGEGLLK AGSIAGTAVL EVTSIEPFGV NQTTITGVQV APVTYLRVSS QPKLYTAQGR TLSAFPLGMS LTFTVQFYNS IGEKFHTHNT QLYLALN

Highest antigen sequence identity to the following orthologs - mouse 91%, rat 91%.

Target Information

Nup210L (nuclear pore membrane glycoprotein 210-like) is a 1,888 amino acid single-pass membrane protein that belongs to the NUP210 family. The gene that encodes Nup210L consists of approximately 162,432 bases and maps to human chromosome 1q21.3. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.