Thermo Fisher Scientific CD20 Monoclonal Antibody (LT20), Biotin
인간 CD20 항원에 특이적인 Mouse IgG2a 단클론 항체로, Biotin으로 표지되어 있습니다. Flow Cytometry에 적합하며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 2–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LT20 |
| Immunogen | Normal human lymphocytes from lymph node |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071557 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of CD20 (Bp35), a 33–37 kDa non-glycosylated membrane receptor with four transmembrane domains. It is expressed on B lymphocytes (lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.
Target Information
CD20 is a non-glycosylated surface phosphoprotein (33–37 kDa) expressed on mature and most malignant B cells, a subpopulation of T lymphocytes, and follicular dendritic cells. It regulates transmembrane calcium conductance, cell cycle progression, and B-cell proliferation. CD20 remains on the cell surface after monoclonal antibody treatment, making it a valuable target for antibody-mediated B-cell depletion in research on B-cell malignancies and immune deficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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