Thermo Fisher Scientific CD4 Monoclonal Antibody (MEM-241), Biotin
인간 CD4 항원을 인식하는 마우스 단클론 항체로, 비오틴으로 표지됨. Western blot과 유세포분석(Flow cytometry)에 사용 가능. 1 mg/mL 농도의 액상 형태로 PBS(pH 7.4) 버퍼에 보관. 보조 T세포 및 단핵구 등에서 CD4 발현 연구에 적합.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-241 |
| Immunogen | Two N-terminal domains of human CD4 fused to human IgG1 Fc |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1072275 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of the CD4 antigen, a 55 kDa transmembrane glycoprotein expressed on a subset of T lymphocytes (“helper” T-cells) as well as on monocytes, tissue macrophages, and granulocytes.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and serves as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but may also be found in monocytes, macrophages, and dendritic cells. Tissue-level expression includes thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 functions in T-cell activation via association with the T-cell receptor complex and the protein tyrosine kinase Lck, and may mediate neuronal damage in immune-related CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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