
Thermo Fisher Scientific Tyrosinase Polyclonal Antibody
Rabbit polyclonal antibody against Human Tyrosinase for Western blot applications. Recognizes multiple species with high predicted reactivity. Supplied as a liquid at 1 mg/mL. Store at 4°C short term or -20°C long term. For research use only.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 225–489 of Human Tyrosinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544800 |
Product Specific Information
- Recommended positive control: U87-MG
- Predicted reactivity: Mouse (91%), Rat (93%), Dog (91%), Pig (94%), Rabbit (93%), Chicken (80%), Sheep (93%), Bovine (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The enzyme encoded by this gene catalyzes the first two steps, and at least one subsequent step, in the conversion of tyrosine to melanin. It has both tyrosine hydroxylase and dopa oxidase catalytic activities and requires copper for function. Mutations in this gene cause oculocutaneous albinism, while nonpathologic polymorphisms contribute to skin pigmentation variation. The human genome contains a pseudogene similar to the 3′ half of this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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